Ozempic® (semaglutide) is a diabetes medication that gained popularity for its weight loss benefits. However, due to high demand, supply shortages and price increases have pushed many to seek safe and effective alternatives.
If you’re in the UK and looking for options beyond Ozempic, you’re in the right place.
💊 1. Wegovy® (Semaglutide 2.4mg)
✅ Best for: High-performance, long-term weight loss
- Same active ingredient as Ozempic
- MHRA-approved in the UK for weight loss
- Taken as a weekly injection
- Helps reduce appetite and food intake
People lose 15–20% of their body weight on Wegovy with proper use.
Price: From £169/month
Prescription Required: ✔️ Yes
💉 2. Saxenda® (Liraglutide)
✅ Best for: Daily support and appetite control
- Once-daily injectable GLP‑1
- Reduces hunger and helps control cravings
- Approved for weight loss in the UK since 2017
- Suitable for those not ready for Wegovy or Ozempic
Users lose around 5–10% of body weight over 3–6 months.
Price: From £129/month
Prescription Required: ✔️ Yes
💊 3. Orlistat (Xenical 120mg)
✅ Best for: Blocking fat absorption from food
- Prescription weight loss pill
- Blocks up to 30% of dietary fat
- Does not affect appetite or mood
- Available as prescription or OTC (60mg)
Can support modest weight loss of 5–7% with diet adjustment.
Price: From £39.99/month
Prescription Required: ❌ OTC for 60mg, ✔️ for 120mg
💉 4. Mounjaro® (Tirzepatide)
✅ Best for: Dual-action weight and blood sugar control (future-forward)
- Combines GLP‑1 and GIP agonist
- More effective than Ozempic in recent studies
- Expected to become widely available in the UK in late 2025
- Currently available via private clinics and special import
Users see up to 22.5% body weight loss — the highest of any medication so far.
Price: From £250–£350/month
Prescription Required: ✔️ Yes (Special Access)
💊 5. Saxenda vs Wegovy vs Orlistat – Quick Comparison
| Feature | Wegovy | Saxenda | Orlistat |
|---|---|---|---|
| Type | Weekly injection | Daily injection | Oral capsule |
| Weight Loss | 15–20% | 5–10% | 4–7% |
| Appetite Control | ✅ Strong | ✅ Moderate | ❌ None |
| Fat Blocking | ❌ | ❌ | ✅ Yes |
| Prescription | ✔️ Required | ✔️ Required | ❌ (for 60mg) |
🔎 Bonus: Natural Alternatives (with Limited Evidence)
- Glucomannan Fibre Capsules – may help with fullness
- Green Tea Extract – mild fat-burning effect
- Caffeine-based Thermogenics – increase metabolism short-term
Note: Natural supplements are not clinically proven like prescription medications and should be used with caution.
✅ Conclusion: What’s the Best Ozempic Alternative for You?
If you’re looking for a true Ozempic substitute, Wegovy offers identical benefits — and is fully approved in the UK.
For daily control and flexibility, Saxenda is still a strong contender.
If you want non-injectable options, Orlistat offers fat-blocking power, and Mounjaro is a rising star in the weight loss world.
🎯 Best Choice:
- 👉 For strong appetite suppression: Wegovy
- 👉 For milder needs or affordability: Orlistat
- 👉 For future access & enhanced results: Mounjaro (Tirzepatide)
