Description
What is Contrave?
Contrave® is a combination oral weight loss medication containing:
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Bupropion – an antidepressant that also helps reduce food cravings
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Naltrexone – commonly used to treat addiction and helps control reward-related eating
Together, they act on the brain’s hunger and reward centres to reduce cravings, emotional eating, and appetite, leading to steady weight loss when combined with a low-calorie diet and exercise.
💡 Key Benefits
✅ Suppresses appetite and reduces hunger
✅ Targets reward-driven/emotional eating
✅ Helps break food addiction patterns
✅ Once-daily oral tablet
✅ FDA & EMA approved (as Mysimba® in EU)
⚕️ Who Is It For?
Contrave (Mysimba) is prescribed to adults with:
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A BMI ≥30 (obese), or
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A BMI ≥27 (overweight) with at least one weight-related condition such as:
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Type 2 diabetes
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Hypertension
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High cholesterol
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Sleep apnoea
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✔️ Ideal for patients who struggle with cravings, emotional eating, or have failed with other treatments.
❌ Who Should NOT Take Contrave
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Pregnant or breastfeeding women
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Individuals with seizure disorders
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Patients with uncontrolled hypertension
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Those taking MAO inhibitors or opioid medications
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Anyone with a history of bulimia or anorexia nervosa
📈 How It Works
Contrave targets the brain’s appetite regulation and reward system:
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Bupropion increases dopamine and norepinephrine to reduce cravings
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Naltrexone blocks opioid receptors linked to pleasure from eating
This dual-action approach helps reduce both physical hunger and emotional triggers for overeating.
💊 Dosage & Titration Schedule
Contrave must be started gradually to reduce side effects:
Week | Dosage |
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Week 1 | 1 tablet in the morning |
Week 2 | 1 tablet morning + 1 tablet evening |
Week 3 | 2 tablets in the morning + 1 in the evening |
Week 4+ | 2 tablets morning + 2 evening (max 4/day) |
💡 Always take with food, preferably not high-fat meals.
📦 What’s Included
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112 tablets (28-day supply at full dose)
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Online consultation with UK prescriber
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Usage and titration guide
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Optional monthly refill program
💷 Sample Pricing (UK)
Pack Size | Price (GBP) |
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14-day starter pack | £89.00 |
28-day full dose pack (112 tablets) | £149.00 |
3-month supply | £399.00 |
Prices may vary depending on supply, availability, and regulatory sourcing (as Contrave or Mysimba).
⚠️ Side Effects
Common:
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Nausea
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Headache
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Dry mouth
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Dizziness
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Constipation or insomnia
Rare (seek medical attention):
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Seizures (risk increases with dose and certain conditions)
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Mood changes or suicidal thoughts
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Allergic reactions
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Increased blood pressure
🧊 Storage
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Store below 25°C
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Keep in original packaging
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Keep away from moisture and heat
📜 Important Information
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Contrave is a prescription-only medicine (POM)
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It is not licensed in the UK as Contrave but may be prescribed as Mysimba® under special order
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Requires an online consultation and review by a UK-licensed prescriber
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Ongoing monitoring is recommended throughout treatment
🔐 Why Buy From Us
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✅ UK-Registered Online Clinic
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📦 Fast, Discreet UK Delivery
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👩⚕️ Licensed UK Prescribers
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💬 Ongoing Weight Loss Support
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🔄 Repeat Prescription Service Available
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